Study Reveals Common Genetic Roots of Psychiatric Disorders

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A recent study has identified shared genetic variants among eight psychiatric disorders, suggesting a potential unified approach to treatment. Researchers from the University of North Carolina discovered that conditions including autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia share a common genetic basis. This revelation builds on previous findings where 109 genes linked to these conditions were identified, demonstrating why many exhibit overlapping symptoms. "The proteins produced by these genes are highly connected to other proteins," stated geneticist Hyejung Won, emphasizing that alterations in these proteins could lead to extensive brain effects. The team analyzed nearly 18,000 genetic variations, identifying 683 variants affecting gene regulation during brain development, raising hopes that understanding these genetic components will foster targeted therapeutic strategies. This research, published in the journal Cell, underscores that approximately 1 in 8 individuals live with a psychiatric condition, highlighting the significance of developing effective interventions targeting shared genetic factors.

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