Revolutionary Brain-On-A-Chip Technology Advances Alzheimer's Research

PTPortugal|

Researchers at the International Iberian Nanotechnology Laboratory in Braga, Portugal, have developed a groundbreaking brain-on-a-chip technology aimed at enhancing treatments for neurological disorders, particularly Alzheimer's disease. Funded by the European Union, this advanced microchip mimics the human brain's complex functions and has the potential to significantly improve the effectiveness of new therapeutic approaches.

The unique device, created as part of the two-year BrainChip4MED project, is designed to overcome the challenges posed by the blood-brain barrier, a protective membrane that prevents many drugs from effectively reaching the brain. By recreating this barrier using bioorganic materials, researchers can more accurately test how medications penetrate the brain, thereby addressing a critical obstacle in developing new Alzheimer's drugs.

Currently, only four drugs are commercially available for Alzheimer's, none of which address the root causes of the disease. The brain-on-a-chip technology not only offers a more ethical alternative to animal testing but also allows for real-time monitoring of drug efficacy in a controlled environment.

The research team, led by Dr. Raquel Rodrigues, stresses the importance of finding new treatments to combat Alzheimer's, which affects approximately 165 million Europeans. The innovative chip will undergo further testing before it can be utilized in human medicine, but the researchers remain optimistic about its potential to revolutionize neurological research.

Weekly Newsletter

Loading...

More from Portugal

Ai Weiwei Navigates Exile While Emphasizing Art Over Wealth

Chinese artist Ai Weiwei, now residing in Portugal's Alentejo region, spoke candidly about his life and art during a recent interview with EL PAÍS. At 67, Weiwei, who has become one of the world's most sought-after artists, has purchased his first home and expresses a dispassionate view on wealth, stating that “money... is very poisonous. You’re only worth as much as your work.” His new 17-acre property is a significant investment; in China, property ownership is scarce and he refers to this ownership as “like a miracle.” Weiwei's background is steeped in political turmoil; he was imprisoned for 81 days in 2011 and has faced constant surveillance from the Chinese government. He uses his art as a platform for political expression, aiming to give voice to the marginalized. His current exhibition, titled "Don Quixote," confronts themes of identity and societal absurdities as he continues to challenge oppressive structures through his work. Weiwei commented, "I act as a loudspeaker for thousands of people who aren’t given a voice,” reinforcing his role as both an artist and an outspoken critic.
PTPortugal

Aga Khan IV, Spiritual Leader of Ismaili Muslims, Passes Away at 88

Prince Karim Aga Khan IV, the spiritual leader of the Ismaili Muslim community and a prominent philanthropist, has died at the age of 88 in Portugal, surrounded by family, according to a statement from the Aga Khan Foundation. Known as a direct descendant of the Prophet Muhammad, the Aga Khan became leader of the Ismailis at just 20 years old while still studying at Harvard University. Widely respected for his philanthropic efforts, the Aga Khan developed a vast network focused on health care, education, and rural economic development. He was known for his contributions to healthcare in several countries, including Bangladesh, Tajikistan, and Afghanistan. His work also included the establishment of architecture programs at prominent institutions such as MIT and Harvard, and the restoration of historic Islamic structures. The Ismaili community, which has expanded from its origins in India to significant numbers in East Africa, Central and South Asia, is anticipated to announce his successor in the coming days, as stated by officials closely associated with the Aga Khan's legacy.
PTPortugal

Aga Khan IV, Spiritual Leader of Ismaili Muslims, Dies at 88

Prince Karim Aga Khan IV, revered by his followers as a direct descendant of the Prophet Muhammad, has passed away at the age of 88 in Portugal. The Aga Khan, who became the spiritual leader of millions of Ismaili Muslims at just 20 years old, was known for his extensive philanthropic work through the Aga Khan Development Network, focusing on health care, education, and economic development in underserved regions. His death was announced by the Aga Khan Foundation and the Ismaili community, which stated that details regarding his successor will be revealed later. Aga Khan IV was educated at Harvard and took on leadership following his grandfather's unexpected decision to pass over his father. He was instrumental in building a network of hospitals and schools in countries like Afghanistan and Bangladesh, significantly impacting local economies. Beyond his spiritual role, he balanced business and philanthropy, accumulating a vast financial empire. The Aga Khan was also known for promoting Islamic culture and fostering dialogue between Muslim societies and the West. He is survived by three sons and a daughter.
PTPortugal
All Portugal News ->