Phage Therapy: A Promising Solution Against Antibiotic-Resistant Superbugs

ESSpain|

A revolutionary battle is emerging in the fight against antibiotic-resistant superbugs, with scientists reviving phage therapy, a method that utilizes bacteriophage viruses to target and eliminate resistant bacteria. The World Health Organization ranks antibiotic resistance as one of the most significant global health threats, potentially leading to 208 million deaths over the next 25 years.

Traditionally, phage therapy has shown effectiveness over the past century, although it fell into obscurity in Western medicine with the rise of antibiotics. Recent studies from the United States, Europe, and the Middle East indicate a revival of interest, with Belgium establishing a national phage bank and the University of California launching a center specifically for phage applications.

Dr. María del Mar Tomás, a microbiologist from the A Coruña University Hospital Complex in Spain, highlights the ubiquitous presence of phages in the environment, suggesting that they could transform treatment for chronic infections caused by persistent bacteria. Early results indicate that over 50% of patients in studies have shown improvement after phage treatment, with 79% experiencing clinical improvement according to a review published in The Lancet Infectious Diseases.

Phage therapy is highly personalized, tailored to target specific bacterial strains in individual patients, thus reducing collateral damage to the body's normal flora. Additionally, it has been demonstrated that phages can enhance the efficacy of existing antibiotics. However, challenges remain, including regulatory hurdles and the need for extensive clinical trials.

Despite skepticism about its efficacy within the scientific community, experts agree on the potential of phage therapy as a viable alternative in the ongoing battle against antibiotic resistance. Researchers are advocating for enhanced regulatory frameworks to facilitate the broader application of phage treatments and unlock their full therapeutic potential.

Weekly Newsletter

Loading...

More from Spain

Major Breakthrough in Evolutionary Biology Reveals Path from Simple to Complex Cells

A new study has unveiled insights into how simple cells evolved into complex life forms over two billion years ago. Conducted by researchers from Spain and published in the journal PNAS, the research attributes this evolutionary leap to the limitations in protein size, which forced an essential shift in genetic regulation, as explained by co-author Jordi Bascompte of the University of Zurich. Historically, the transition from prokaryotic cells (simple bacteria) to eukaryotic cells (more complex organisms) has puzzled scientists. Bascompte cites British biochemist Nick Lane's assertion regarding the lack of known intermediaries between these cellular forms. The research posits that as proteins could no longer elongate effectively, cells began utilizing non-coding parts of DNA, such as introns, leading to new genetic regulatory strategies. Biotechnologist César de la Fuente from the University of Pennsylvania praised the study's interdisciplinary approach, noting its potential to explain the complexity of multicellular organisms. The collaborative effort from various scientific disciplines reflects a quest for answers that has spanned three decades, illustrating the intricate relationship between biology and computational algorithms.
ESSpain

Glaciers Losing Ice at Alarming Rate, Warns World Meteorological Organization

The World Meteorological Organization (WMO) has issued a stark warning that the world's glaciers are losing ice at an unprecedented rate, equating to three Olympic-sized swimming pools every second. This announcement coincides with the first World Glacier Day on March 21, amidst the International Year of Glaciers’ Conservation. According to the WMO Secretary-General Celeste Saulo, the rapid retreat of glaciers presents a serious threat to global economies and ecosystems, with implications reaching far beyond mountain regions. Recent research published in *Nature*, led by the World Glacier Monitoring Service, reveals that glaciers have lost an average of 273 billion tons of ice annually since 2000, with a 36% increase in ice loss in the last decade. This study indicates that glaciers in regions like the Alps and Pyrenees have suffered the most, with potential long-term impacts on freshwater supplies, particularly in Asia. The report emphasizes the urgent need for climate action, as failing to mitigate further warming could result in the loss of many glaciers globally by the end of the century, potentially raising sea levels by 30–35 centimeters.
ESSpain

Luis Rubiales Found Guilty of Sexual Assault in Hermoso Case

Former Spanish football chief Luis Rubiales has been found guilty of sexually assaulting player Jenni Hermoso by kissing her without consent after the Women's World Cup final in August 2023. Spain's High Court has ordered Rubiales to pay a fine exceeding €10,000 (approximately $11,000) but acquitted him of coercion, according to court documents. During the trial, Hermoso testified that she "never" consented to the kiss, calling the incident a "taint" on what was otherwise "one of the happiest days" of her life. Rubiales, 47, claimed the kiss was consensual and occurred in a "moment of jubilation." However, the controversy overshadowed Spain's historic victory, prompting widespread discussions around sexism in sports and the push for equal treatment of female athletes. The case and its ramifications have sparked significant public debate and advocacy for greater accountability and respect for women in sports. The ruling marks a pivotal moment in the evolving conversation about consent and harassment in the sporting world.
ESSpain
All Spain News ->