New Bat Coronavirus Discovered in China Poses Potential Human Health Risk

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Researchers in China have identified a new bat coronavirus named HKU5-CoV-2, which may pose a risk of transmission from animals to humans. The study, published in the journal Cell, indicates that this virus can bind to the human angiotensin-converting enzyme 2 (ACE2) receptor, similar to the mechanism used by SARS-CoV-2, which caused the COVID-19 pandemic.

Led by renowned virologist Shi Zhengli, the research team from the Guangzhou Laboratory, Wuhan University, and other institutions highlighted that HKU5-CoV-2 belongs to the merbecovirus subgenus, which includes the Middle East respiratory syndrome virus. The virus was initially found in Japanese pipistrelle bats in Hong Kong.

While the virus can bind to ACE2 receptors in multiple mammalian species, the efficiency of HKU5-CoV-2 in attaching to human ACE2 is noted to be lower than that of SARS-CoV-2. The researchers cautioned against excessive alarm, stating that while the risk of spillover to humans exists, it should not be overstated.

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