Breakthrough Discovery: Oyster Protein Offers Hope Against Drug-Resistant Bacteria

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Australian researchers have made a significant discovery regarding a protein in the blood of the Sydney rock oyster, Saccostrea glomerata, which could prove effective in combating drug-resistant bacteria. The protein, found in the oyster's haemolymph, demonstrates the ability to kill various harmful bacteria and enhance the efficacy of certain antibiotics.

In laboratory tests, the oyster protein effectively eliminated strains of Streptococcus pneumoniae and Streptococcus pyogenes, known to cause pneumonia and strep throat, respectively. Additionally, when combined with antibiotics such as ampicillin and gentamicin, the protein augmented their effectiveness significantly against other serious bacterial infections.

The emergence of antimicrobial resistance has been described as a major global health crisis, prompting researchers to explore innovative solutions. According to Prof. Kirsten Benkendorff from Southern Cross University, approximately two dozen oysters would supply enough haemolymph to provide a therapeutic dose of the protein for an individual, though further studies are needed to fully harness its potential.

While the findings are promising, Benkendorff cautioned against relying on oyster consumption for antibiotic treatment, as cooking deactivates the protein's antimicrobial properties. The protein's ability to disrupt bacterial biofilms offers additional advantages, potentially aiding in treatment approaches for infections resistant to standard antibiotics.

Experts express enthusiasm about this discovery, highlighting its potential to contribute to the fight against escalating drug-resistant infections. The study has been published in the journal Plos One.

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