Australia's TGA Approves Wegovy for Heart Disease Treatment in Obese Patients

An ongoing coronial inquest into the murder of Lilie James at St Andrew's Cathedral school in Sydney has revealed harrowing footage of her ex-boyfriend, Paul Thijssen, meticulously planning the attack. The inquest heard that James, 23, was found dead in a gymnasium toilet after a water polo training session on October 25, 2023. Thijssen, who had a brief relationship with James that had ended just days prior, took his own life days later, with his body discovered in the ocean. Counsel assisting the New South Wales coroner, Jennifer Single SC, described the footage as "not easy to watch," showing Thijssen rehearsing his attack and locking doors to isolate the gym. James was last seen smiling and interacting with Thijssen upon her return from training, unaware of the impending violence. The inquest revealed tracks of Thijssen's history of stalking and intimidation against previous partners, indicating a pattern of concerning behavior. It continues as authorities seek to understand the events leading to this tragic incident.

Australian researchers from the Children's Medical Research Institute in Sydney have revealed a new mechanism through which telomeres—protective caps at the ends of chromosomes—can defend against cancer. Published in the journal Nature Communications, the study indicates that telomeres do more than merely shorten with age; they also actively respond to stress to trigger cellular aging processes that prevent the development of cancer, as stated by Tony Cesare, a researcher at the institute. According to the research, when cells experience stress, telomeres actively open up, leading to protective responses such as cell cycle arrest or programmed cell death. This discovery challenges the long-standing perception of telomeres as passive entities, positioning them as crucial players in cancer prevention. Collaborating with researchers from the University of Kyoto, the team explored these active functions and their implications for potential cancer treatments. With an estimated 20 million new cancer cases reported globally in 2022, this breakthrough could pave the way for innovative therapeutic strategies that target telomeres to eliminate cancerous cells, possibly transforming cancer management, officials noted.

Authorities in New South Wales have discovered a body in bushland near North Nowra, believed to be that of a six-year-old girl reported missing earlier on Sunday. The girl was last seen on Sunday afternoon, prompting a swift response from police in the South Coast district, who initiated a search operation for her. According to a statement from NSW police, the body was found at approximately 6 PM during the ongoing search efforts. While formal identification has not yet occurred, officials indicated that it is likely to be the missing child. An investigation into the circumstances surrounding the incident is currently underway, and a report will be submitted to the coroner. This tragic event has drawn significant attention, underscoring community concerns for child safety and the challenges faced in search and recovery operations. As details continue to unfold, local authorities have urged anyone with information to come forward to assist in the investigation.